Treatment Patterns Among Adults with Primary Immune Thrombocytopenia Diagnosed in Hematology Clinics in the United States
Authors: M. Alan Brookhart, PhDDiane Reams
View publication →Challenge
The treatment landscape for primary immune thrombocytopenia had expanded with thrombopoietin receptor agonists, but real-world patterns of treatment sequencing, duration, and switching had not been systematically described in a large hematology clinic dataset.
Solution
Target RWE researchers characterized treatment patterns among adults with ITP diagnosed in US hematology clinics using real-world data, describing sequences of conventional and novel agents, duration of therapy, and predictors of treatment modification.
Impact
Documenting real-world ITP treatment sequencing patterns provides Amgen and other hematology sponsors with natural history and competitive context needed to design effectiveness studies and position novel ITP therapies.
Use Cases / Links
ITP treatment sequencing and switching patterns for hematology drug development competitive context, Real-world treatment duration evidence for ITP therapy positioning and label strategy